Age-specific and gender-specific radiation risks in paediatric angiography and interventional cardiology: conversion coefficients and risk reference values.
Br J Radiol
; 93(1110): 20190869, 2020 Jun.
Article
en En
| MEDLINE
| ID: mdl-32242740
ABSTRACT
OBJECTIVES:
To estimate risk for exposure-induced cancer death (REID), organ-specific risks of exposure-induced cancer death (REIDHT) and associated conversion coefficients (CCREIDKAP=REID/kerma-area product (KAP), CCREIDHTKAP=REIDHT/KAP) in paediatric cardiac catheterizations using data from radiation dose structured reports (RDSR). A novel risk surveillance tool consisting of age-specific and gender-specific risk reference values (RRVs) related to population cancer risk is suggested.METHODS:
The PCXMC v.2.0 code is used together with exposure-related information from RDSR from a cohort of 238 children to assess cancer risks and related conversion coefficients. The KAP corresponding to 1 in 1000 of increased REID is used to define age-specific and gender-specific KAP values to monitor risk in such patient cohorts, here denoted as RRVs.RESULTS:
The REID estimates ranged from below 1 up to 300 in 100,000, and the RRVs for the different age groups and gender ranged from 0.77 Gycm2 and 2.1 Gycm2 for neonates (female, male) to 11 Gycm2 and 25 Gycm2 for 15-year-olds (female, male). The CCREIDKAP and CCREIDHTKAP decreased biexponentially with increased age, being notably higher for female patients.CONCLUSIONS:
Prominent risk contributing organs were the lungs and the (female) breast. The concept of age-specific and gender-specific RRVs related to population cancer risk is introduced and is intended to be used as a supporting tool for physicians performing such interventions. ADVANCES IN KNOWLEDGE Age-related and gender-related conversion coefficients for radiation risk, CCREIDKAP and CCREIDHTKAP, are introduced and a novel risk surveillance concept, the RRV, is suggested for paediatric cardiac catheterizations.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Cateterismo Cardíaco
/
Factores Sexuales
/
Factores de Edad
/
Exposición a la Radiación
/
Cardiopatías Congénitas
/
Neoplasias Inducidas por Radiación
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Aspecto:
Determinantes_sociais_saude
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
Idioma:
En
Revista:
Br J Radiol
Año:
2020
Tipo del documento:
Article
País de afiliación:
Suecia