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RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier.
Sarkisjan, Dzjemma; Julsing, Joris R; El Hassouni, Btissame; Honeywell, Richard J; Kathmann, Ietje; Matherly, Larry H; Lee, Young B; Kim, Deog J; Peters, Godefridus J.
Afiliación
  • Sarkisjan D; Laboratory Medical Oncology, Amsterdam UMC, location VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
  • Julsing JR; Laboratory Medical Oncology, Amsterdam UMC, location VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
  • El Hassouni B; Laboratory Medical Oncology, Amsterdam UMC, location VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
  • Honeywell RJ; Laboratory Medical Oncology, Amsterdam UMC, location VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
  • Kathmann I; Laboratory Medical Oncology, Amsterdam UMC, location VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
  • Matherly LH; Department of Oncology, Wayne State University School of Medicine, Detroit, and Molecular Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201-1976, USA.
  • Lee YB; Rexahn Pharmaceuticals, Inc., Rockville, MD 20850, USA.
  • Kim DJ; Rexahn Pharmaceuticals, Inc., Rockville, MD 20850, USA.
  • Peters GJ; Laboratory Medical Oncology, Amsterdam UMC, location VU University Medical Center, 1081 HV Amsterdam, The Netherlands.
Int J Mol Sci ; 21(8)2020 Apr 14.
Article en En | MEDLINE | ID: mdl-32295203

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citidina / Proteínas Supresoras de Tumor / Transportador de Folato Acoplado a Protón / ADN (Citosina-5-)-Metiltransferasa 1 Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Citidina / Proteínas Supresoras de Tumor / Transportador de Folato Acoplado a Protón / ADN (Citosina-5-)-Metiltransferasa 1 Límite: Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Países Bajos
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