Active Contact Forces Drive Nonequilibrium Fluctuations in Membrane Vesicles.
Phys Rev Lett
; 124(15): 158102, 2020 Apr 17.
Article
en En
| MEDLINE
| ID: mdl-32357050
ABSTRACT
We analyze the nonequilibrium shape fluctuations of giant unilamellar vesicles encapsulating motile bacteria. Owing to bacteria-membrane collisions, we experimentally observe a significant increase in the magnitude of membrane fluctuations at low wave numbers, compared to the well-known thermal fluctuation spectrum. We interrogate these results by numerically simulating membrane height fluctuations via a modified Langevin equation, which includes bacteria-membrane contact forces. Taking advantage of the lengthscale and timescale separation of these contact forces and thermal noise, we further corroborate our results with an approximate theoretical solution to the dynamical membrane equations. Our theory and simulations demonstrate excellent agreement with nonequilibrium fluctuations observed in experiments. Moreover, our theory reveals that the fluctuation-dissipation theorem is not broken by the bacteria; rather, membrane fluctuations can be decomposed into thermal and active components.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vesículas Citoplasmáticas
/
Lípidos de la Membrana
/
Modelos Biológicos
/
Modelos Químicos
Idioma:
En
Revista:
Phys Rev Lett
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos