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Positive epistasis between viral polymerase and the 3' untranslated region of its genome reveals the epidemiologic fitness of dengue virus.
Syenina, Ayesa; Vijaykrishna, Dhanasekaran; Gan, Esther Shuyi; Tan, Hwee Cheng; Choy, Milly M; Siriphanitchakorn, Tanamas; Cheng, Colin; Vasudevan, Subhash G; Ooi, Eng Eong.
Afiliación
  • Syenina A; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169857 Singapore.
  • Vijaykrishna D; Saw Swee Hock School of Public Health, National University of Singapore, 117549 Singapore.
  • Gan ES; Department of Microbiology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
  • Tan HC; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169857 Singapore.
  • Choy MM; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169857 Singapore.
  • Siriphanitchakorn T; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169857 Singapore.
  • Cheng C; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169857 Singapore.
  • Vasudevan SG; Department of Biological Sciences, National University of Singapore, 117558 Singapore.
  • Ooi EE; Program in Emerging Infectious Diseases, Duke-National University of Singapore Medical School, 169857 Singapore.
Proc Natl Acad Sci U S A ; 117(20): 11038-11047, 2020 05 19.
Article en En | MEDLINE | ID: mdl-32366663
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 3_ND Problema de salud: 2_cobertura_universal / 2_enfermedades_transmissibles / 3_dengue / 3_neglected_diseases Asunto principal: Proteínas no Estructurales Virales / Regiones no Traducidas 3' / Dengue / Virus del Dengue Límite: Humans País/Región como asunto: Caribe / Puerto rico Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 3_ND Problema de salud: 2_cobertura_universal / 2_enfermedades_transmissibles / 3_dengue / 3_neglected_diseases Asunto principal: Proteínas no Estructurales Virales / Regiones no Traducidas 3' / Dengue / Virus del Dengue Límite: Humans País/Región como asunto: Caribe / Puerto rico Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article