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Influences of ABC transporter and CYP3A4/5 genetic polymorphisms on the pharmacokinetics of lenvatinib in Chinese healthy subjects.
Li, Jiaming; Wang, Xiaoqian; Ning, Chen; Wang, Zhaoyu; Wang, Yao; Zheng, Ming; Zhang, Siliang; Lu, Yang; Zhang, Yongjie; Li, Ning; Chen, Xijing; Zhao, Di.
Afiliación
  • Li J; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Wang X; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Ning C; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Wang Z; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Wang Y; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Zheng M; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, Henan, China.
  • Zhang S; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Lu Y; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Zhang Y; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China.
  • Li N; National Experimental Teaching Demonstration Center of Pharmacy, China Pharmaceutical University, Nanjing, 211198, Jiangsu, China.
  • Chen X; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China. chenxj-lab@hotmail.com.
  • Zhao D; Clinical Pharmacokinetics Laboratory, School of Basic Medicine and Clinical Pharmacy, China Pharmaceutical University, #639 Longmian Avenue, Jiangning District, Nanjing, 211198, China. zh_d99@cpu.edu.cn.
Eur J Clin Pharmacol ; 76(8): 1125-1133, 2020 Aug.
Article en En | MEDLINE | ID: mdl-32382947
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Quinolinas / Transportadoras de Casetes de Unión a ATP / Citocromo P-450 CYP3A / Antineoplásicos Límite: Adult / Female / Humans / Male Idioma: En Revista: Eur J Clin Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Fenilurea / Quinolinas / Transportadoras de Casetes de Unión a ATP / Citocromo P-450 CYP3A / Antineoplásicos Límite: Adult / Female / Humans / Male Idioma: En Revista: Eur J Clin Pharmacol Año: 2020 Tipo del documento: Article País de afiliación: China