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A second-generation glucagon-like peptide-1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models.
Borner, Tito; Shaulson, Evan D; Tinsley, Ian C; Stein, Lauren M; Horn, Charles C; Hayes, Matthew R; Doyle, Robert P; De Jonghe, Bart C.
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  • Borner T; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Shaulson ED; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Tinsley IC; Department of Chemistry, Syracuse University, Syracuse, New York, USA.
  • Stein LM; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Horn CC; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Hayes MR; UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
  • Doyle RP; Center for Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
  • De Jonghe BC; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Diabetes Obes Metab ; 22(10): 1729-1741, 2020 10.
Article en En | MEDLINE | ID: mdl-32410372
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Receptor del Péptido 1 Similar al Glucagón Límite: Animals / Humans Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Diabetes Mellitus Tipo 2 / Receptor del Péptido 1 Similar al Glucagón Límite: Animals / Humans Idioma: En Revista: Diabetes Obes Metab Asunto de la revista: ENDOCRINOLOGIA / METABOLISMO Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos