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Germline variant burden in cancer genes correlates with age at diagnosis and somatic mutation burden.
Qing, Tao; Mohsen, Hussein; Marczyk, Michal; Ye, Yixuan; O'Meara, Tess; Zhao, Hongyu; Townsend, Jeffrey P; Gerstein, Mark; Hatzis, Christos; Kluger, Yuval; Pusztai, Lajos.
Afiliación
  • Qing T; Breast Medical Oncology, School of Medicine, Yale University, New Haven, CT, USA.
  • Mohsen H; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.
  • Marczyk M; Breast Medical Oncology, School of Medicine, Yale University, New Haven, CT, USA.
  • Ye Y; Data Mining Division, Silesian University of Technology, Gliwice, Poland.
  • O'Meara T; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.
  • Zhao H; Breast Medical Oncology, School of Medicine, Yale University, New Haven, CT, USA.
  • Townsend JP; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.
  • Gerstein M; Department of Biostatistics, School of Public Health, Yale University, New Haven, CT, USA.
  • Hatzis C; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.
  • Kluger Y; Department of Biostatistics, School of Public Health, Yale University, New Haven, CT, USA.
  • Pusztai L; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.
Nat Commun ; 11(1): 2438, 2020 05 15.
Article en En | MEDLINE | ID: mdl-32415133
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mutación de Línea Germinal / Neoplasias Límite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Mutación de Línea Germinal / Neoplasias Límite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos