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Activation of Leukopoiesis in Rat Blood with Trimecaine-Based Ionic Compounds.
Baktybayeva, Lyailya; Yu, Valentina; Zazybin, Alexey; Zolotareva, Darya; Dauletbakov, Anuar.
Afiliación
  • Baktybayeva L; Biology and Biotechnology Department, Al-Farabi Kazakh National University, 050040 Almaty, Kazakhstan.
  • Yu V; A. B. Bekturov Institute of Chemical Sciences, 050000 Almaty, Kazakhstan.
  • Zazybin A; Center of Chemical Engineering, Kazakh-British Technical University, 050000 Almaty, Kazakhstan.
  • Zolotareva D; Center of Chemical Engineering, Kazakh-British Technical University, 050000 Almaty, Kazakhstan.
  • Dauletbakov A; School of Chemical & Biochemical Engineering, Satbayev University, 050013 Almaty, Kazakhstan.
Biomed Res Int ; 2020: 7636290, 2020.
Article en En | MEDLINE | ID: mdl-32420370
ABSTRACT
A study of myelostimulating activity of ionic compounds-trimecaine alkyl iodide derivatives under the cipher BIV (BIV-117, BIV-118, and BIV-119) was conducted on a model of doxorubicin pancytopenia in white laboratory rats. It was established that the compounds BIV-117 and BIV-119 had a pronounced leukopoiesis-stimulating activity, exceeding the activity of the methyluracil as a comparison drug. Compounds BIV-117 and BIV-119 had erythropoiesis- and thrombocytopoiesis-stimulating activity at the level of methyluracil.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trimecaína / Leucopoyesis Límite: Animals Idioma: En Revista: Biomed Res Int Año: 2020 Tipo del documento: Article País de afiliación: Kazajstán
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trimecaína / Leucopoyesis Límite: Animals Idioma: En Revista: Biomed Res Int Año: 2020 Tipo del documento: Article País de afiliación: Kazajstán