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Heterologous Expression and Functional Characterization of Novel CYP2C9 Variants Identified in the Alaska Native People.
McDonald, Matthew G; Henderson, Lindsay M; Ray, Sutapa; Yeung, Catherine K; Johnson, Amanda L; Kowalski, John P; Hanenberg, Helmut; Wiek, Constanze; Thummel, Kenneth E; Rettie, Allan E.
Afiliación
  • McDonald MG; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Henderson LM; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Ray S; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Yeung CK; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Johnson AL; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Kowalski JP; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Hanenberg H; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Wiek C; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Thummel KE; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
  • Rettie AE; Departments of Medicinal Chemistry (M.G.M., S.R., A.L.J., J.P.K., A.E.R.), Pharmaceutics (L.M.H., K.E.T.), and Pharmacy (C.K.Y.), University of Washington, Seattle, Washington; Department of Otorhinolaryngology and Head/Neck Surgery, Heinrich-Heine University, Düsseldorf, Germany (H.H., C.W.); and D
J Pharmacol Exp Ther ; 374(2): 233-240, 2020 08.
Article en En | MEDLINE | ID: mdl-32423989
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 3_ND Problema de salud: 1_acesso_equitativo_servicos / 1_desigualdade_iniquidade / 3_neglected_diseases / 3_zoonosis Asunto principal: Citocromo P-450 CYP2C9 / Pueblos Indígenas Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: J Pharmacol Exp Ther Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 3_ND Problema de salud: 1_acesso_equitativo_servicos / 1_desigualdade_iniquidade / 3_neglected_diseases / 3_zoonosis Asunto principal: Citocromo P-450 CYP2C9 / Pueblos Indígenas Límite: Humans País/Región como asunto: America do norte Idioma: En Revista: J Pharmacol Exp Ther Año: 2020 Tipo del documento: Article