MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF-&#954;B activation.

Liu, Xuejiao; Yue, Chenglong; Shi, Lin; Liu, Guanzheng; Cao, Qiyu; Shan, Qianqian; Wang, Yifeng; Chen, Xiangyu; Li, Huan; Wang, Jie; Gao, Shangfeng; Niu, Mingshan; Yu, Rutong

MALT1 is a potential therapeutic target in glioblastoma and plays a crucial role in EGFR-induced NF-κB activation.

Liu, Xuejiao; Yue, Chenglong; Shi, Lin; Liu, Guanzheng; Cao, Qiyu; Shan, Qianqian; Wang, Yifeng; Chen, Xiangyu; Li, Huan; Wang, Jie; Gao, Shangfeng; Niu, Mingshan; Yu, Rutong.

Afiliación

Liu X; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Yue C; Department of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Shi L; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Liu G; Surgical Deparment 9, Xuzhou Children's Hospital, Xuzhou, China.
Cao Q; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Shan Q; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Wang Y; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Chen X; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Li H; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Wang J; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Gao S; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Niu M; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.
Yu R; Insititute of Nervous System Diseases, Xuzhou Medical University, Xuzhou, China.

J Cell Mol Med ; 24(13): 7550-7562, 2020 07.

Article en En | MEDLINE | ID: mdl-32452133

Asunto(s)

Receptores ErbB/metabolismo; Glioblastoma/metabolismo; Terapia Molecular Dirigida; Proteína 1 de la Translocación del Linfoma del Tejido Linfático Asociado a Mucosas/metabolismo; FN-kappa B/metabolismo; Animales; Puntos de Control del Ciclo Celular/efectos de los fármacos; Puntos de Control del Ciclo Celular/genética; Línea Celular Tumoral; Movimiento Celular/efectos de los fármacos; Movimiento Celular/genética; Proliferación Celular/efectos de los fármacos; Proliferación Celular/genética; Factor de Crecimiento Epidérmico/farmacología; Glioblastoma/patología; Humanos; Ratones Noqueados; Proteína 1 de la Translocación del Linfoma del Tejido Linfático Asociado a Mucosas/antagonistas & inhibidores; Invasividad Neoplásica; Ensayo de Tumor de Célula Madre

Palabras clave

EGFR/ NF-κB signalling pathway; GBM; MALT1; MI-2; cell proliferation

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: FN-kappa B / Glioblastoma / Terapia Molecular Dirigida / Receptores ErbB / Proteína 1 de la Translocación del Linfoma del Tejido Linfático Asociado a Mucosas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Cell Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2020 Tipo del documento: Article País de afiliación: China

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