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Generation of pralatrexate resistant T-cell lymphoma lines reveals two patterns of acquired drug resistance that is overcome with epigenetic modifiers.
Scotto, Luigi; Kinahan, Cristina; Casadei, Beatrice; Mangone, Michael; Douglass, Eugene; Murty, Vundavalli V; Marchi, Enrica; Ma, Helen; George, Changchun; Montanari, Francesca; Califano, Andrea; O'Connor, Owen A.
Afiliación
  • Scotto L; Center for Lymphoid Malignancies, Columbia University Medical Center, New York, New York, USA.
  • Kinahan C; Division of Experimental Therapeutics, Columbia University Medical Center, New York, New York, USA.
  • Casadei B; Center for Lymphoid Malignancies, Columbia University Medical Center, New York, New York, USA.
  • Mangone M; Division of Experimental Therapeutics, Columbia University Medical Center, New York, New York, USA.
  • Douglass E; Center for Lymphoid Malignancies, Columbia University Medical Center, New York, New York, USA.
  • Murty VV; Division of Experimental Therapeutics, Columbia University Medical Center, New York, New York, USA.
  • Marchi E; Center for Lymphoid Malignancies, Columbia University Medical Center, New York, New York, USA.
  • Ma H; Division of Experimental Therapeutics, Columbia University Medical Center, New York, New York, USA.
  • George C; Department of Systems Biology, Columbia University Medical Center, New York, New York, USA.
  • Montanari F; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA.
  • Califano A; Center for Lymphoid Malignancies, Columbia University Medical Center, New York, New York, USA.
  • O'Connor OA; Division of Experimental Therapeutics, Columbia University Medical Center, New York, New York, USA.
Genes Chromosomes Cancer ; 59(11): 639-651, 2020 11.
Article en En | MEDLINE | ID: mdl-32614991
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfoma de Células T / Resistencia a Antineoplásicos / Epigénesis Genética Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Genes Chromosomes Cancer Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfoma de Células T / Resistencia a Antineoplásicos / Epigénesis Genética Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Genes Chromosomes Cancer Asunto de la revista: BIOLOGIA MOLECULAR / NEOPLASIAS Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos