Role of DNA damage in the progress of chronic tubule­interstitial injury.

Sun, Linxiao; Zhu, Xiandong; Luo, Jiao; Wang, Cheng; Chen, Bicheng

Role of DNA damage in the progress of chronic tubuleinterstitial injury.

Sun, Linxiao; Zhu, Xiandong; Luo, Jiao; Wang, Cheng; Chen, Bicheng.

Afiliación

Sun L; Key Laboratory of Diagnosis and Treatment of Severe HepatoPancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Zhu X; Key Laboratory of Diagnosis and Treatment of Severe HepatoPancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Luo J; Department of Laboratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, P.R. China.
Wang C; Key Laboratory of Diagnosis and Treatment of Severe HepatoPancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.
Chen B; Key Laboratory of Diagnosis and Treatment of Severe HepatoPancreatic Diseases of Zhejiang Province, Zhejiang Provincial Top Key Discipline in Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China.

Mol Med Rep ; 22(2): 1081-1089, 2020 08.

Article en En | MEDLINE | ID: mdl-32626982

Asunto(s)

Daño del ADN/fisiología; Fibrosis/genética; Túbulos Renales/metabolismo; Apoptosis/genética; Ácidos Aristolóquicos/toxicidad; Proteínas de la Ataxia Telangiectasia Mutada/genética; Proteínas de la Ataxia Telangiectasia Mutada/metabolismo; Ciclo Celular/genética; Muerte Celular/genética; Línea Celular; Proliferación Celular/genética; Enfermedad Crónica; Inhibidor p21 de las Quinasas Dependientes de la Ciclina/metabolismo; Daño del ADN/genética; Reparación del ADN/genética; Reparación del ADN/fisiología; Células Epiteliales/metabolismo; Fibrosis/inducido químicamente; Fibrosis/metabolismo; Técnicas de Silenciamiento del Gen; Humanos; Túbulos Renales/lesiones; Serpinas/metabolismo; Transducción de Señal; Proteína p53 Supresora de Tumor/metabolismo

Palabras clave

cell proliferation; cell death; dna damage response; p21; tubulointerstitial fibrosis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Daño del ADN / Fibrosis / Túbulos Renales Límite: Humans Idioma: En Revista: Mol Med Rep Año: 2020 Tipo del documento: Article

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