Proteomic and transcriptomic profiling identifies mediators of anchorage-independent growth and roles of inhibitor of differentiation proteins in invasive lobular carcinoma.

Tasdemir, Nilgun; Ding, Kai; Savariau, Laura; Levine, Kevin M; Du, Tian; Elangovan, Ashuvinee; Bossart, Emily A; Lee, Adrian V; Davidson, Nancy E; Oesterreich, Steffi

Tasdemir, Nilgun; Ding, Kai; Savariau, Laura; Levine, Kevin M; Du, Tian; Elangovan, Ashuvinee; Bossart, Emily A; Lee, Adrian V; Davidson, Nancy E; Oesterreich, Steffi.

Afiliación

Tasdemir N; Women's Cancer Research Center, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center (HCC), Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.
Ding K; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.
Savariau L; Women's Cancer Research Center, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center (HCC), Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.
Levine KM; Integrative Systems Biology Program, University of Pittsburgh, Pittsburgh, PA, USA.
Du T; Women's Cancer Research Center, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center (HCC), Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.
Elangovan A; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, 15261, USA.
Bossart EA; Women's Cancer Research Center, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center (HCC), Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.
Lee AV; Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15261, USA.
Davidson NE; Women's Cancer Research Center, University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center (HCC), Magee-Womens Research Institute, 204 Craft Avenue, Pittsburgh, PA, 15213, USA.
Oesterreich S; School of Medicine, Tsinghua University, Beijing, 100084, China.

Sci Rep ; 10(1): 11487, 2020 07 13.

Article en En | MEDLINE | ID: mdl-32661241

Asunto(s)

Neoplasias de la Mama/genética; Carcinoma Lobular/genética; Proteómica; Transcriptoma/genética; Autoantígenos/genética; Neoplasias de la Mama/patología; Cadherinas/genética; Carcinoma Lobular/patología; Diferenciación Celular/genética; Femenino; Regulación Neoplásica de la Expresión Génica/genética; Humanos; Proteína 1 Inhibidora de la Diferenciación/genética; Proteínas Inhibidoras de la Diferenciación/genética; Péptidos y Proteínas de Señalización Intracelular/genética; Proteínas de la Membrana/genética; Persona de Mediana Edad; Invasividad Neoplásica/genética; Invasividad Neoplásica/patología; Proteínas de Neoplasias/genética; Fosfatidilinositol 3-Quinasas/genética; Proteínas Proto-Oncogénicas c-akt/genética; Proteínas Quinasas S6 Ribosómicas 90-kDa/genética; Transducción de Señal/genética

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Carcinoma Lobular / Proteómica / Transcriptoma Tipo de estudio: Prognostic_studies Límite: Female / Humans / Middle aged Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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