Insulin sensing by astrocytes is critical for normal thermogenesis and body temperature regulation.

Manaserh, Iyad H; Maly, Emily; Jahromi, Marziyeh; Chikkamenahalli, Lakshmikanth; Park, Joshua; Hill, Jennifer

Manaserh, Iyad H; Maly, Emily; Jahromi, Marziyeh; Chikkamenahalli, Lakshmikanth; Park, Joshua; Hill, Jennifer.

Afiliación

Manaserh IH; Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA.
Maly E; Center for Diabetes and Endocrine Research, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA.
Jahromi M; Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA.
Chikkamenahalli L; Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA.
Park J; Department of Physiology and Pharmacology, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA.
Hill J; Department of Neuroscience, College of Medicine and Life Sciences, The University of Toledo, Toledo, Ohio, USA.

J Endocrinol ; 247(1): 39-52, 2020 10.

Article en En | MEDLINE | ID: mdl-32698146

Asunto(s)

Astrocitos/fisiología; Regulación de la Temperatura Corporal/fisiología; Insulina/metabolismo; Receptor de Insulina/fisiología; Termogénesis/fisiología; Adipocitos/fisiología; Tejido Adiposo Pardo/fisiología; Animales; Astrocitos/química; Diabetes Mellitus Tipo 2; Metabolismo Energético/fisiología; Femenino; Proteína Ácida Fibrilar de la Glía/genética; Masculino; Ratones; Ratones Endogámicos C57BL; Ratones Noqueados; Obesidad; Receptor de Insulina/deficiencia; Receptor de Insulina/genética; Factores Sexuales; Transducción de Señal/fisiología

Palabras clave

B3-adrenergic signaling; astrocytic insulin signaling; body temperature; systemic metabolism

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Regulación de la Temperatura Corporal / Receptor de Insulina / Astrocitos / Termogénesis / Insulina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Endocrinol Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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