Point-of-care tests for malaria: speeding up the diagnostics at the bedside and challenges in malaria cases detection.
Diagn Microbiol Infect Dis
; 98(3): 115122, 2020 Nov.
Article
en En
| MEDLINE
| ID: mdl-32711185
ABSTRACT
Malaria remains as one of the major public health problems worldwide. About 228 million cases occurred in 2018 only, with Africa bearing about 93% of the cases. Asymptomatic population carrying the various forms of the parasite Plasmodium in endemic areas plays an important role in the spread of the disease. To tackle this battle, more sensitive and precise detection kits for malaria are crucial to better control the number of new malaria cases. In this review, we not only discuss some of the available approaches to rapidly detect new malaria cases in endemic areas but also shed light on parallel problems that may affect the detection of individuals infected with the parasite, covering kelch 13 mutation, glucose 6-phosphate dehydrogenase deficiency, and hemoglobin disorders. Available approaches for malaria detection covered in this review are focused on point-of-care tests, including portable polymerase chain reaction and aptamers.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
/
3_ND
Problema de salud:
2_enfermedades_transmissibles
/
3_malaria
/
3_neglected_diseases
Asunto principal:
Pruebas en el Punto de Atención
/
Malaria
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Diagn Microbiol Infect Dis
Año:
2020
Tipo del documento:
Article
País de afiliación:
Brasil