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A multimodal treatment of carbon ions irradiation, miRNA-34 and mTOR inhibitor specifically control high-grade chondrosarcoma cancer stem cells.
Vares, Guillaume; Ahire, Vidhula; Sunada, Shigeaki; Ho Kim, Eun; Sai, Sei; Chevalier, François; Romeo, Paul-Henri; Yamamoto, Tadashi; Nakajima, Tetsuo; Saintigny, Yannick.
Afiliación
  • Vares G; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan. Electronic address: guillaume.vares@oist.jp.
  • Ahire V; Research Laboratory and Open Facility for Radiation Biology with Accelerated Ions (LARIA), CEA/DRF/IBFJ/IRCM, Caen, France; Centre de Recherche sur les Ions, les Matériaux et la Photonique (CIMAP), Normandie Univ/ENSICAEN/UNICAEN/CEA/CNRS, Caen, France.
  • Sunada S; Department of Radiation Effects Research, National Institutes for Quantum and Radiological Science and Technology (QST), Chiba, Japan; Department of Molecular Genetics, Tokyo Medical and Dental University (TMDU), Japan.
  • Ho Kim E; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, South Korea.
  • Sai S; Department of Charged Particle Therapy Research, National Institutes for Quantum and Radiological Science and Technology (QST), Chiba, Japan.
  • Chevalier F; Research Laboratory and Open Facility for Radiation Biology with Accelerated Ions (LARIA), CEA/DRF/IBFJ/IRCM, Caen, France; Centre de Recherche sur les Ions, les Matériaux et la Photonique (CIMAP), Normandie Univ/ENSICAEN/UNICAEN/CEA/CNRS, Caen, France.
  • Romeo PH; Research Laboratory on Repair and Transcription in Hematopoietic Stem Cells (LRTS), François Jacob Institute of Biology, CEA/DRF/IBFJ/IRCM, Fontenay-aux-Roses, France.
  • Yamamoto T; Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Japan.
  • Nakajima T; Department of Radiation Effects Research, National Institutes for Quantum and Radiological Science and Technology (QST), Chiba, Japan.
  • Saintigny Y; Research Laboratory and Open Facility for Radiation Biology with Accelerated Ions (LARIA), CEA/DRF/IBFJ/IRCM, Caen, France; Centre de Recherche sur les Ions, les Matériaux et la Photonique (CIMAP), Normandie Univ/ENSICAEN/UNICAEN/CEA/CNRS, Caen, France. Electronic address: yannick.saintigny@cea.fr.
Radiother Oncol ; 150: 253-261, 2020 09.
Article en En | MEDLINE | ID: mdl-32717360
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 2_ODS3 Problema de salud: 1_doencas_nao_transmissiveis / 2_muertes_prematuras_enfermedades_notrasmisibles Asunto principal: Neoplasias Óseas / Condrosarcoma / MicroARNs Límite: Humans Idioma: En Revista: Radiother Oncol Año: 2020 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 / 2_ODS3 Problema de salud: 1_doencas_nao_transmissiveis / 2_muertes_prematuras_enfermedades_notrasmisibles Asunto principal: Neoplasias Óseas / Condrosarcoma / MicroARNs Límite: Humans Idioma: En Revista: Radiother Oncol Año: 2020 Tipo del documento: Article