Systemic sclerosis-associated interstitial lung disease.
Curr Opin Pulm Med
; 26(5): 487-495, 2020 09.
Article
en En
| MEDLINE
| ID: mdl-32740379
ABSTRACT
PURPOSE OF REVIEW In this review, the authors discuss systemic sclerosis-associated interstitial lung disease (SSc-ILD) with a focus on recent developments in diagnosis, surveillance, and management. RECENT FINDINGS:
With advances in the management of SSc, the importance of ILD has been increasingly recognized and is the leading cause of mortality. Early detection is essential, and a combination of lung function testing and chest imaging are key tools in diagnosis and surveillance. The foundation of treatment is immunomodulation with recent studies identifying several potential new agents. The use of therapies targeting pro-fibrotic pathways have demonstrated significant effects on lung function decline and represent the latest advance in therapy for SSc-ILD.SUMMARY:
Recent studies support the use of newer therapies in SSc-ILD including antifibrotic agents. The identification and management of comorbidities is important, and lung transplantation is a viable option for patients with advanced disease.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
2_ODS3
/
6_ODS3_enfermedades_notrasmisibles
Problema de salud:
2_muertes_prematuras_enfermedades_notrasmisibles
/
6_immune_disorders
/
6_musculoskeletal_diseases_rheumatic_disorders
/
6_other_respiratory_diseases
/
6_skin_diseases
Asunto principal:
Esclerodermia Sistémica
/
Enfermedades Pulmonares Intersticiales
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Humans
Idioma:
En
Revista:
Curr Opin Pulm Med
Año:
2020
Tipo del documento:
Article
País de afiliación:
Canadá