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An injectable hydrogel-formulated inhibitor of prolyl-4-hydroxylase promotes T regulatory cell recruitment and enhances alveolar bone regeneration during resolution of experimental periodontitis.
Nagai, Kosuke; Ideguchi, Hidetaka; Kajikawa, Tetsuhiro; Li, Xiaofei; Chavakis, Triantafyllos; Cheng, Jing; Messersmith, Phillip B; Heber-Katz, Ellen; Hajishengallis, George.
Afiliación
  • Nagai K; Laboratory of Innate Immunity and Inflammation, Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Ideguchi H; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Kajikawa T; Laboratory of Innate Immunity and Inflammation, Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Li X; Department of Pathophysiology - Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
  • Chavakis T; Laboratory of Innate Immunity and Inflammation, Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Cheng J; Laboratory of Innate Immunity and Inflammation, Department of Basic and Translational Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Messersmith PB; Institute of Clinical Chemistry and Laboratory Medicine, Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.
  • Heber-Katz E; Department of Bioengineering, University of California, Berkeley, Berkeley, CA, USA.
  • Hajishengallis G; Department of Materials Science and Engineering, University of California, Berkeley, Berkeley, CA, USA.
FASEB J ; 34(10): 13726-13740, 2020 10.
Article en En | MEDLINE | ID: mdl-32812255
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Periodontitis / Regeneración Ósea / Linfocitos T Reguladores / Hidrogeles / Inhibidores Enzimáticos / Prolina Dioxigenasas del Factor Inducible por Hipoxia Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Periodontitis / Regeneración Ósea / Linfocitos T Reguladores / Hidrogeles / Inhibidores Enzimáticos / Prolina Dioxigenasas del Factor Inducible por Hipoxia Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: FASEB J Asunto de la revista: BIOLOGIA / FISIOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos