Lytic Cell Death Mechanisms in Human Respiratory Syncytial Virus-Infected Macrophages: Roles of Pyroptosis and Necroptosis.

Bedient, Lori; Pokharel, Swechha Mainali; Chiok, Kim R; Mohanty, Indira; Beach, Sierra S; Miura, Tanya A; Bose, Santanu

Bedient, Lori; Pokharel, Swechha Mainali; Chiok, Kim R; Mohanty, Indira; Beach, Sierra S; Miura, Tanya A; Bose, Santanu.

Afiliación

Bedient L; Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Pokharel SM; Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Chiok KR; Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Mohanty I; Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.
Beach SS; Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA.
Miura TA; Department of Biological Sciences, University of Idaho, Moscow, ID 83844, USA.
Bose S; Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164, USA.

Viruses ; 12(9)2020 08 25.

Article en En | MEDLINE | ID: mdl-32854254

Asunto(s)

Macrófagos/patología; Necroptosis; Piroptosis; Virus Sincitial Respiratorio Humano/patogenicidad; Proteínas Adaptadoras de Señalización CARD/metabolismo; Caspasa 1/metabolismo; Muerte Celular; Humanos; Inflamasomas/metabolismo; L-Lactato Deshidrogenasa/metabolismo; Macrófagos/metabolismo; Macrófagos/virología; Proteína con Dominio Pirina 3 de la Familia NLR/metabolismo; Proteínas Quinasas/metabolismo; Especies Reactivas de Oxígeno/metabolismo; Proteína Serina-Treonina Quinasas de Interacción con Receptores/metabolismo; Células THP-1

Palabras clave

RSV; lytic cell death; macrophages; necroptosis; pyroptosis; respiratory syncytial virus

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Virus Sincitial Respiratorio Humano / Piroptosis / Necroptosis / Macrófagos Límite: Humans Idioma: En Revista: Viruses Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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