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Quantifying drug tissue biodistribution by integrating high content screening with deep-learning analysis.
Li, Zhuyin; Xiao, Youping; Peng, Jia; Locke, Darren; Holmes, Derek; Li, Lei; Hamilton, Shannon; Cook, Erica; Myer, Larnie; Vanderwall, Dana; Cloutier, Normand; Siddiqui, Akbar M; Whitehead, Paul; Bishop, Richard; Zhao, Lei; Cvijic, Mary Ellen.
Afiliación
  • Li Z; Lead Discovery and Optimization, Bristol-Myers Squibb, 3551 Lawrenceville Road, Princeton, NJ, 08540, USA. Zhuyin.Li@bms.com.
  • Xiao Y; Information Technology for R&D, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Peng J; Lead Discovery and Optimization, Bristol-Myers Squibb, 3551 Lawrenceville Road, Princeton, NJ, 08540, USA.
  • Locke D; Translational Medicine, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Holmes D; Immunoscience Biology Discovery, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Li L; Lead Discovery and Optimization, Bristol-Myers Squibb, 3551 Lawrenceville Road, Princeton, NJ, 08540, USA.
  • Hamilton S; Lead Discovery and Optimization, Bristol-Myers Squibb, 3551 Lawrenceville Road, Princeton, NJ, 08540, USA.
  • Cook E; Lead Discovery and Optimization, Bristol-Myers Squibb, 3551 Lawrenceville Road, Princeton, NJ, 08540, USA.
  • Myer L; Lead Discovery and Optimization, Bristol-Myers Squibb, 3551 Lawrenceville Road, Princeton, NJ, 08540, USA.
  • Vanderwall D; Information Technology for R&D, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Cloutier N; Information Technology for R&D, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Siddiqui AM; Information Technology for R&D, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Whitehead P; Information Technology for R&D, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Bishop R; Information Technology for R&D, Bristol-Myers Squibb, Princeton, NJ, USA.
  • Zhao L; Cardiovascular Translational Research, Bristol-Myers Squibb, Hopewell, NJ, USA.
  • Cvijic ME; Lead Discovery and Optimization, Bristol-Myers Squibb, 3551 Lawrenceville Road, Princeton, NJ, 08540, USA.
Sci Rep ; 10(1): 14408, 2020 09 01.
Article en En | MEDLINE | ID: mdl-32873881
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento de Imagen Asistido por Computador / Carbocianinas / Cadherinas / Inmunoconjugados / Ensayos Analíticos de Alto Rendimiento / Colorantes Fluorescentes / Aprendizaje Profundo Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Procesamiento de Imagen Asistido por Computador / Carbocianinas / Cadherinas / Inmunoconjugados / Ensayos Analíticos de Alto Rendimiento / Colorantes Fluorescentes / Aprendizaje Profundo Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals Idioma: En Revista: Sci Rep Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos