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Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial.
Angus, Derek C; Derde, Lennie; Al-Beidh, Farah; Annane, Djillali; Arabi, Yaseen; Beane, Abigail; van Bentum-Puijk, Wilma; Berry, Lindsay; Bhimani, Zahra; Bonten, Marc; Bradbury, Charlotte; Brunkhorst, Frank; Buxton, Meredith; Buzgau, Adrian; Cheng, Allen C; de Jong, Menno; Detry, Michelle; Estcourt, Lise; Fitzgerald, Mark; Goossens, Herman; Green, Cameron; Haniffa, Rashan; Higgins, Alisa M; Horvat, Christopher; Hullegie, Sebastiaan J; Kruger, Peter; Lamontagne, Francois; Lawler, Patrick R; Linstrum, Kelsey; Litton, Edward; Lorenzi, Elizabeth; Marshall, John; McAuley, Daniel; McGlothin, Anna; McGuinness, Shay; McVerry, Bryan; Montgomery, Stephanie; Mouncey, Paul; Murthy, Srinivas; Nichol, Alistair; Parke, Rachael; Parker, Jane; Rowan, Kathryn; Sanil, Ashish; Santos, Marlene; Saunders, Christina; Seymour, Christopher; Turner, Anne; van de Veerdonk, Frank; Venkatesh, Balasubramanian.
Afiliación
  • Angus DC; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Derde L; The UPMC Health System Office of Healthcare Innovation, Pittsburgh, Pennsylvania.
  • Al-Beidh F; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Annane D; Intensive Care Center, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Arabi Y; Division of Anaesthetics, Pain Medicine and Intensive Care Medicine, Department of Surgery and Cancer, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom.
  • Beane A; Intensive Care Unit, Raymond Poincaré Hospital (AP-HP), Paris, France.
  • van Bentum-Puijk W; Simone Veil School of Medicine, University of Versailles, Versailles, France.
  • Berry L; University Paris Saclay, Garches, France.
  • Bhimani Z; Intensive Care Department, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
  • Bonten M; Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
  • Bradbury C; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Brunkhorst F; Berry Consultants LLC, Austin, Texas.
  • Buxton M; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
  • Buzgau A; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Cheng AC; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • de Jong M; Bristol Royal Informatory, Bristol, United Kingdom.
  • Detry M; University of Bristol, Bristol, United Kingdom.
  • Estcourt L; Center for Clinical Studies and Center for Sepsis Control and Care (CSCC), Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.
  • Fitzgerald M; Global Coalition for Adaptive Research, San Francisco, California.
  • Goossens H; Helix, Monash University, Melbourne, Victoria, Australia.
  • Green C; Infection Prevention and Healthcare Epidemiology Unit, Alfred Health, Melbourne, Victoria, Australia.
  • Haniffa R; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
  • Higgins AM; Department of Medical Microbiology, Amsterdam University Medical Center, University of Amsterdam, the Netherlands.
  • Horvat C; Berry Consultants LLC, Austin, Texas.
  • Hullegie SJ; NHS Blood and Transplant, Bristol, United Kingdom.
  • Kruger P; Transfusion Medicine, Medical Sciences Division, University of Oxford, Oxford, United Kingdom.
  • Lamontagne F; Berry Consultants LLC, Austin, Texas.
  • Lawler PR; Department of Microbiology, Antwerp University Hospital, Antwerp, Belgium.
  • Linstrum K; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
  • Litton E; Network for Improving Critical Care Systems and Training, Colombo, Sri Lanka.
  • Lorenzi E; Mahidol Oxford Tropical Medicine Research Unit, Bangkok, Thailand.
  • Marshall J; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
  • McAuley D; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • McGlothin A; The UPMC Health System Office of Healthcare Innovation, Pittsburgh, Pennsylvania.
  • McGuinness S; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
  • McVerry B; Intensive Care Unit, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
  • Montgomery S; Université de Sherbrooke, Sherbrooke, Quebec, Canada.
  • Mouncey P; Cardiac Intensive Care Unit, Peter Munk Cardiac Centre, University Health Network, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.
  • Murthy S; The Clinical Research Investigation and Systems Modeling of Acute Illness (CRISMA) Center, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
  • Nichol A; School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia.
  • Parke R; Berry Consultants LLC, Austin, Texas.
  • Parker J; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada.
  • Rowan K; Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada.
  • Sanil A; Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom.
  • Santos M; Berry Consultants LLC, Austin, Texas.
  • Saunders C; Australian and New Zealand Intensive Care Research Centre, School of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
  • Seymour C; Cardiothoracic and Vascular Intensive Care Unit, Auckland City Hospital, Auckland, New Zealand.
  • Turner A; The Health Research Council of New Zealand, Wellington, New Zealand.
  • van de Veerdonk F; Medical Research Institute of New Zealand, Wellington, New Zealand.
  • Venkatesh B; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
JAMA ; 324(13): 1317-1329, 2020 10 06.
Article en En | MEDLINE | ID: mdl-32876697
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 4_TD / 6_ODS3_enfermedades_notrasmisibles Problema de salud: 4_covid_19 / 4_pneumonia / 6_other_respiratory_diseases Asunto principal: Neumonía Viral / Respiración Artificial / Hidrocortisona / Infecciones por Coronavirus / Antiinflamatorios Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 4_TD / 6_ODS3_enfermedades_notrasmisibles Problema de salud: 4_covid_19 / 4_pneumonia / 6_other_respiratory_diseases Asunto principal: Neumonía Viral / Respiración Artificial / Hidrocortisona / Infecciones por Coronavirus / Antiinflamatorios Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: JAMA Año: 2020 Tipo del documento: Article