A Homodimeric Aptamer Variant Generated from Ligand-Guided Selection Activates the T Cell Receptor Cluster of Differentiation 3 Complex.

Freage, Lina; Jamal, Deana; Williams, Nicole B; Mallikaratchy, Prabodhika R

Freage, Lina; Jamal, Deana; Williams, Nicole B; Mallikaratchy, Prabodhika R.

Afiliación

Freage L; Department of Chemistry, Lehman College, The City University of New York, 250 Bedford Park Blvd. West, Bronx, NY 10468, USA.
Jamal D; Department of Chemistry, Lehman College, The City University of New York, 250 Bedford Park Blvd. West, Bronx, NY 10468, USA.
Williams NB; PhD Program in Molecular, Cellular and Developmental Biology, CUNY Graduate Center, 365 Fifth Avenue, New York, NY 10016, USA.
Mallikaratchy PR; Department of Chemistry, Lehman College, The City University of New York, 250 Bedford Park Blvd. West, Bronx, NY 10468, USA; PhD Programs in Chemistry and Biochemistry, CUNY Graduate Center, 365 Fifth Avenue, New York, NY 10016, USA; PhD Program in Molecular, Cellular and Developmental Biology, CUNY

Mol Ther Nucleic Acids ; 22: 167-178, 2020 Aug 19.

Article en En | MEDLINE | ID: mdl-32920262

Palabras clave

LIGS; SELEX; T cells; T-cell activation; TCR complex; aptamers; cell binding; dimeric aptamer; immunotherapy; nucleic acids

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Mol Ther Nucleic Acids Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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