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Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker.
Duvall, Bridget; Zimmermann, Sarah C; Gao, Run-Duo; Thomas, Ajit G; Kalcic, Filip; Veeravalli, Vijayabhaskar; Elgogary, Amira; Rais, Rana; Rojas, Camilo; Le, Anne; Slusher, Barbara S; Tsukamoto, Takashi.
Afiliación
  • Duvall B; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Zimmermann SC; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Gao RD; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Thomas AG; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Kalcic F; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Veeravalli V; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Elgogary A; Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Rais R; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Rojas C; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Le A; Department of Pathology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Slusher BS; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
  • Tsukamoto T; Johns Hopkins Drug Discovery, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA. Electronic address: ttsukamoto@jhmi.edu.
Bioorg Med Chem ; 28(20): 115698, 2020 10 15.
Article en En | MEDLINE | ID: mdl-33069080
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Sulfhidrilo / Derivados del Benceno / Inhibidores Enzimáticos / Glutaminasa / Riñón Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Compuestos de Sulfhidrilo / Derivados del Benceno / Inhibidores Enzimáticos / Glutaminasa / Riñón Límite: Humans Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos