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CYP154C5 Regioselectivity in Steroid Hydroxylation Explored by Substrate Modifications and Protein Engineering*.
Bracco, Paula; Wijma, Hein J; Nicolai, Bastian; Buitrago, Jhon Alexander Rodriguez; Klünemann, Thomas; Vila, Agustina; Schrepfer, Patrick; Blankenfeldt, Wulf; Janssen, Dick B; Schallmey, Anett.
Afiliación
  • Bracco P; Biocatalysis, Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
  • Wijma HJ; Department of Biochemistry Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, Netherlands.
  • Nicolai B; Biocatalysis, Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
  • Buitrago JAR; Institute for Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig, Spielmannstr. 7, 38106, Braunschweig, Germany.
  • Klünemann T; Structure and Function of Proteins, Helmholtz Centre for Infection Research, Inhoffenstr. 7, 38124, Braunschweig, Germany.
  • Vila A; Biocatalysis, Institute of Biotechnology, RWTH Aachen University, Worringerweg 3, 52074, Aachen, Germany.
  • Schrepfer P; Institute for Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig, Spielmannstr. 7, 38106, Braunschweig, Germany.
  • Blankenfeldt W; Structure and Function of Proteins, Helmholtz Centre for Infection Research, Inhoffenstr. 7, 38124, Braunschweig, Germany.
  • Janssen DB; Institute for Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig, Spielmannstr. 7, 38106, Braunschweig, Germany.
  • Schallmey A; Department of Biochemistry Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, Netherlands.
Chembiochem ; 22(6): 1099-1110, 2021 03 16.
Article en En | MEDLINE | ID: mdl-33145893
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esteroides / Proteínas Bacterianas / Ingeniería de Proteínas / Sistema Enzimático del Citocromo P-450 Idioma: En Revista: Chembiochem Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Esteroides / Proteínas Bacterianas / Ingeniería de Proteínas / Sistema Enzimático del Citocromo P-450 Idioma: En Revista: Chembiochem Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Alemania