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Nicotine exhausts CD8+ T cells against tumor cells through increasing miR-629-5p to repress IL2RB-mediated granzyme B expression.
Cheng, Chun-Chia; Lin, Hsin-Chi; Chiang, Ya-Wen; Chang, Jungshan; Sie, Zong-Lin; Yang, Bi-Ling; Lim, Ken-Hong; Peng, Cheng-Liang; Ho, Ai-Sheng; Chang, Yi-Fang.
Afiliación
  • Cheng CC; Radiation Biology Research Center, Institute for Radiological Research, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taiwan.
  • Lin HC; Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, Taiwan.
  • Chiang YW; Division of Hematology and Oncology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
  • Chang J; Department of Medical Research, Laboratory of Good Clinical Research Center, Mackay Memorial Hospital, Tamsui District, New Taipei City, Taiwan.
  • Sie ZL; Graduate Institute of Medical Sciences, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
  • Yang BL; Radiation Biology Research Center, Institute for Radiological Research, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taiwan.
  • Lim KH; Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, Taiwan.
  • Peng CL; Division of Hematology and Oncology, Department of Internal Medicine, Mackay Memorial Hospital, Taipei, Taiwan.
  • Ho AS; Department of Medical Research, Laboratory of Good Clinical Research Center, Mackay Memorial Hospital, Tamsui District, New Taipei City, Taiwan.
  • Chang YF; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.
Cancer Immunol Immunother ; 70(5): 1351-1364, 2021 May.
Article en En | MEDLINE | ID: mdl-33146402
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / MicroARNs / Subunidad beta del Receptor de Interleucina-2 / Adenocarcinoma del Pulmón / Nicotina Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2021 Tipo del documento: Article País de afiliación: Taiwán
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T CD8-positivos / MicroARNs / Subunidad beta del Receptor de Interleucina-2 / Adenocarcinoma del Pulmón / Nicotina Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2021 Tipo del documento: Article País de afiliación: Taiwán