A double blind randomized controlled trial using copper impregnated maternity sanitary towels to reduce perineal wound infection.
Midwifery
; 92: 102858, 2021 Jan.
Article
en En
| MEDLINE
| ID: mdl-33157498
ABSTRACT
OBJECTIVE:
To investigate the effect of copper impregnated sanitary towels on the infection rate following vaginal delivery (VD).DESIGN:
Single center double blind randomized controlled trial.PARTICIPANTS:
Women aged 18 or over who had a sutured second-degree tear or episiotomy following VD.INTERVENTIONS:
All women were randomized to receive either a copper-oxide impregnated sanitary towel (study group) or a non-copper sanitary towel (control group). MAIN OUTCOMEMEASURES:
The primary study outcome was the incidence of wound infection within a 30-day period from VD, assessed via telephone questionnaire. Secondary outcomes were length of hospital stay and risk factors of infection.RESULTS:
450 women were enrolled in the study of whom 225 were randomized to the copper impregnated sanitary towel (study group) and 225 to the non-copper sanitary towel (control group) group. Follow-up rate was 98.2%. A total of 102 women (23.1%) developed an infection within 30 days following VD, 19 in the study group (8.6%) and 83 (37.4%) in the control group (P = <0.001, absolute risk reduction (ARR) of 28.8%). The incidence of superficial/deep and organ/space infections was significantly lower in the study group (7.7% vs. 30.2%, P = <0.001 and 4.6% vs. 31.5%, P = <0.001 respectively) with an ARR of 22.5% and 27.0% respectively. Multivariable analysis reported Asian ethnicity and prolonged rupture of membranes as significant risk factors; for the development of infection (OR 1.91, P = 0.03 and OR = 1.97, P = 0.04 respectively).CONCLUSIONS:
This is the first study to demonstrate a significant reduction in infection rate following VD with the use of copper impregnated sanitary towels.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
Problema de salud:
1_doencas_transmissiveis
Asunto principal:
Perineo
/
Infección de la Herida Quirúrgica
/
Cobre
/
Episiotomía
/
Productos para la Higiene Menstrual
Tipo de estudio:
Clinical_trials
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Midwifery
Asunto de la revista:
ENFERMAGEM
/
OBSTETRICIA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Reino Unido