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Development of autotaxin inhibitors: A series of tetrazole cinnamides.
Thomson, Christopher G; Le Grand, Darren; Dowling, Mark; Beattie, David; Elphick, Lucy; Faller, Michael; Freeman, Mark; Hardaker, Elizabeth; Head, Victoria; Hemmig, Rene; Hill, Johan; Lister, Andrew; Pascoe, David; Rieffel, Sebastien; Shrestha, Binesh; Steward, Oliver; Zink, Florence.
Afiliación
  • Thomson CG; Global Discovery Chemistry, Novartis Institutes For Biomedical Research, Horsham, UK. Electronic address: chris.thomson@pharmaron-uk.com.
  • Le Grand D; Global Discovery Chemistry, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Dowling M; Respiratory Disease Area, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Beattie D; Global Discovery Chemistry, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Elphick L; Respiratory Disease Area, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Faller M; Department of Chemical Biology and Therapeutics, Novartis Institutes For Biomedical Research, Basel, Switzerland.
  • Freeman M; Respiratory Disease Area, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Hardaker E; Respiratory Disease Area, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Head V; Metabolism and Pharmacokinetics, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Hemmig R; Department of Chemical Biology and Therapeutics, Novartis Institutes For Biomedical Research, Basel, Switzerland.
  • Hill J; Respiratory Disease Area, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Lister A; Global Discovery Chemistry, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Pascoe D; Global Discovery Chemistry, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Rieffel S; Department of Chemical Biology and Therapeutics, Novartis Institutes For Biomedical Research, Basel, Switzerland.
  • Shrestha B; Department of Chemical Biology and Therapeutics, Novartis Institutes For Biomedical Research, Basel, Switzerland.
  • Steward O; Global Discovery Chemistry, Novartis Institutes For Biomedical Research, Horsham, UK.
  • Zink F; Department of Chemical Biology and Therapeutics, Novartis Institutes For Biomedical Research, Basel, Switzerland.
Bioorg Med Chem Lett ; 31: 127663, 2021 01 01.
Article en En | MEDLINE | ID: mdl-33160025
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tetrazoles / Cinamatos / Hidrolasas Diéster Fosfóricas / Inhibidores Enzimáticos / Desarrollo de Medicamentos / Amidas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tetrazoles / Cinamatos / Hidrolasas Diéster Fosfóricas / Inhibidores Enzimáticos / Desarrollo de Medicamentos / Amidas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article