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PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts.
Piberger, Ann Liza; Bowry, Akhil; Kelly, Richard D W; Walker, Alexandra K; González-Acosta, Daniel; Bailey, Laura J; Doherty, Aidan J; Méndez, Juan; Morris, Joanna R; Bryant, Helen E; Petermann, Eva.
Afiliación
  • Piberger AL; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. A.L.Piberger@bham.ac.uk.
  • Bowry A; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Kelly RDW; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Walker AK; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • González-Acosta D; Molecular Oncology Program, Spanish National Cancer Research Centre, Madrid, Spain.
  • Bailey LJ; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9RQ, UK.
  • Doherty AJ; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9RQ, UK.
  • Méndez J; Molecular Oncology Program, Spanish National Cancer Research Centre, Madrid, Spain.
  • Morris JR; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Bryant HE; Department of Oncology & Metabolism, The Medical School, University of Sheffield, Sheffield, S10 2RX, UK.
  • Petermann E; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK. E.Petermann@bham.ac.uk.
Nat Commun ; 11(1): 5863, 2020 11 17.
Article en En | MEDLINE | ID: mdl-33203852

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aductos de ADN / ADN Primasa / ADN Polimerasa Dirigida por ADN / Recombinación Homóloga / Enzimas Multifuncionales Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Aductos de ADN / ADN Primasa / ADN Polimerasa Dirigida por ADN / Recombinación Homóloga / Enzimas Multifuncionales Límite: Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido
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