Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFR&#945;1 for Specific Infection of Breast Cancer Cells.

Hall, Bonnie L; Leronni, Daniela; Miyagawa, Yoshitaka; Goins, William F; Glorioso, Joseph C; Cohen, Justus B

Generation of an Oncolytic Herpes Simplex Viral Vector Completely Retargeted to the GDNF Receptor GFRα1 for Specific Infection of Breast Cancer Cells.

Hall, Bonnie L; Leronni, Daniela; Miyagawa, Yoshitaka; Goins, William F; Glorioso, Joseph C; Cohen, Justus B.

Afiliación

Hall BL; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA.
Leronni D; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA.
Miyagawa Y; Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15219, USA.
Goins WF; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA.
Glorioso JC; Department of Biochemistry and Molecular Biology, Nippon Medical School, Tokyo 113-0031, Japan.
Cohen JB; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA 15219, USA.

Int J Mol Sci ; 21(22)2020 Nov 21.

Article en En | MEDLINE | ID: mdl-33233403

Asunto(s)

Neoplasias de la Mama/terapia; Receptores del Factor Neurotrófico Derivado de la Línea Celular Glial/genética; Nectinas/genética; Simplexvirus/genética; Animales; Neoplasias de la Mama/genética; Neoplasias de la Mama/patología; Chlorocebus aethiops; Femenino; Regulación Neoplásica de la Expresión Génica; Vectores Genéticos/genética; Vectores Genéticos/uso terapéutico; Humanos; Células MCF-7; Viroterapia Oncolítica/métodos; Virus Oncolíticos/genética; Unión Proteica/genética; Células Vero

Palabras clave

breast cancer; herpes simplex virus; oncolytic

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_breast_cancer / 6_oral_conditions_disorders Asunto principal: Neoplasias de la Mama / Simplexvirus / Receptores del Factor Neurotrófico Derivado de la Línea Celular Glial / Nectinas Límite: Animals / Female / Humans Idioma: En Revista: Int J Mol Sci Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

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