The Center Cannot Hold: NRF2 Battles Ferroptosis in the 3rd Dimension.
Mol Cell
; 80(5): 760-761, 2020 12 03.
Article
en En
| MEDLINE
| ID: mdl-33275886
ABSTRACT
Takahashi et al. (2020) conduct a focused CRISPR/Cas9 screen against NRF2 target and other redox regulatory genes in both 2D- and 3D-culture systems, uncovering a vulnerability of spheroid cancer cells deprived of extracellular matrix to undergo ferroptosis.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Factor 2 Relacionado con NF-E2
/
Ferroptosis
Idioma:
En
Revista:
Mol Cell
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2020
Tipo del documento:
Article
País de afiliación:
Estados Unidos