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The JAK1 Selective Inhibitor ABT 317 Blocks Signaling Through Interferon-γ and Common γ Chain Cytokine Receptors to Reverse Autoimmune Diabetes in NOD Mice.
Ge, Tingting; Jhala, Gaurang; Fynch, Stacey; Akazawa, Satoru; Litwak, Sara; Pappas, Evan G; Catterall, Tara; Vakil, Ishan; Long, Andrew J; Olson, Lisa M; Krishnamurthy, Balasubramanian; Kay, Thomas W; Thomas, Helen E.
Afiliación
  • Ge T; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Jhala G; Department of Medicine, St Vincent's Hospital, The University of Melbourne, Fitzroy, VIC, Australia.
  • Fynch S; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Akazawa S; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Litwak S; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Pappas EG; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Catterall T; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Vakil I; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Long AJ; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
  • Olson LM; Department of Medicine, St Vincent's Hospital, The University of Melbourne, Fitzroy, VIC, Australia.
  • Krishnamurthy B; AbbVie Bioresearch Center, Worcester, MA, United States.
  • Kay TW; AbbVie Bioresearch Center, Worcester, MA, United States.
  • Thomas HE; Immunology and Diabetes Unit, St Vincent's Institute, Fitzroy, VIC, Australia.
Front Immunol ; 11: 588543, 2020.
Article en En | MEDLINE | ID: mdl-33343569
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interferón gamma / Diabetes Mellitus Tipo 1 / Janus Quinasa 1 / Subunidad gamma Común de Receptores de Interleucina / Inhibidores de las Cinasas Janus Límite: Animals Idioma: En Revista: Front Immunol Año: 2020 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Interferón gamma / Diabetes Mellitus Tipo 1 / Janus Quinasa 1 / Subunidad gamma Común de Receptores de Interleucina / Inhibidores de las Cinasas Janus Límite: Animals Idioma: En Revista: Front Immunol Año: 2020 Tipo del documento: Article País de afiliación: Australia