Muscle fiber size in healthy children and adults in relation to sex and fiber types.
Muscle Nerve
; 63(4): 586-592, 2021 04.
Article
en En
| MEDLINE
| ID: mdl-33347630
ABSTRACT
BACKGROUND:
In adult males, cross-sectional area (CSA) for type II muscle fibers is generally larger than for type I fibers. In this cross-sectional study the aim was to compare sex-related CSAs of various muscle fiber types during childhood-to-adulthood transition.METHODS:
Percutaneous biopsy samples were obtained from vastus lateralis in 10-y-old children (10 males and 5 females) and in young adults (9 males and 7 females). Fiber types were classified by myofibrillar ATPase and CSAs from NADH-dehydrogenase staining.RESULTS:
Type IIA were larger than type I fibers in adult males, but not in adult females or children (age x sex x fiber type, P < .002). When including all participants, body weight and sex explained 78% of the variation in type IIA CSA but only body weight contributed for type I.CONCLUSIONS:
Sex-specific patterns in CSA of the muscle fiber types appears to develop during the transition from childhood to adulthood.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Factores Sexuales
/
Músculo Esquelético
/
Fibras Musculares Esqueléticas
/
Músculo Cuádriceps
Tipo de estudio:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Muscle Nerve
Año:
2021
Tipo del documento:
Article
País de afiliación:
Suecia