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Host fibrinogen drives antimicrobial function in Staphylococcus aureus peritonitis through bacterial-mediated prothrombin activation.
Prasad, Joni M; Negrón, Oscar; Du, Xinli; Mullins, Eric S; Palumbo, Joseph S; Gilbertie, Jessica M; Höök, Magnus; Grover, Steven P; Pawlinski, Rafal; Mackman, Nigel; Degen, Jay L; Flick, Matthew J.
Afiliación
  • Prasad JM; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229.
  • Negrón O; Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, and the UNC Blood Research Center, University of North Carolina, Chapel Hill, NC 27599.
  • Du X; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229.
  • Mullins ES; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229.
  • Palumbo JS; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229.
  • Gilbertie JM; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606.
  • Höök M; Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technologies, Texas A&M Health Sciences Center, Houston, TX 77030.
  • Grover SP; Department of Medicine, Lineberger Comprehensive Cancer Center, and the UNC Blood Research Center, University of North Carolina, Chapel Hill, NC 27599.
  • Pawlinski R; Department of Medicine, Lineberger Comprehensive Cancer Center, and the UNC Blood Research Center, University of North Carolina, Chapel Hill, NC 27599.
  • Mackman N; Department of Medicine, Lineberger Comprehensive Cancer Center, and the UNC Blood Research Center, University of North Carolina, Chapel Hill, NC 27599.
  • Degen JL; Cancer and Blood Disease Institute, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229.
  • Flick MJ; Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, and the UNC Blood Research Center, University of North Carolina, Chapel Hill, NC 27599; matthew_flick@med.unc.edu.
Proc Natl Acad Sci U S A ; 118(1)2021 01 05.
Article en En | MEDLINE | ID: mdl-33443167
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_digestive_diseases / 6_other_malignant_neoplasms Asunto principal: Peritonitis / Fibrinógeno / Protrombina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_digestive_diseases / 6_other_malignant_neoplasms Asunto principal: Peritonitis / Fibrinógeno / Protrombina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2021 Tipo del documento: Article