Evaluation of Therapeutic Effects on Collateral Circulation in Patients with Chronic Leriche Syndrome: a Case-Control Study of Intraluminal Stent Implantation and Surgical Bypass Grafting.
Cardiovasc Intervent Radiol
; 44(4): 550-557, 2021 Apr.
Article
en En
| MEDLINE
| ID: mdl-33447923
ABSTRACT
PURPOSE:
The aim of the study was to compare the hemodynamic effects of endoluminal and open surgical treatment of chronic Leriche syndrome using arterial collaterals on CTA as a surrogate parameter. MATERIALS ANDMETHODS:
This retrospective, single-center study included 30 patients with chronic Leriche syndrome. Fourteen patients underwent intraluminal stent implantation (endo group), and sixteen underwent surgical bypass grafting (surgical group). CTA was performed pre- and postoperatively, and a series of evaluation parameters (a1 sum of area of the systemic collateral pathways in the abdominal wall before operation, a2 sum of area of the systemic collateral pathways in the abdominal wall after operation, ar area of lumen of the stent or artificial vessel, BSR post- and preoperative blood supply ratio = (a2 + ar)/a1, RR reduction rate of systemic collateral arteries after the operation = (a1-a2)/a1) were defined to quantitatively evaluate the hemodynamic effects of the treatments. Short-term clinical outcomes, including improvement of symptoms, postoperative complications and in-hospital stay, were also collected. Then, the effects of the two operations were compared.RESULTS:
There was no significant difference in the baseline (a1, p = 0.301) and postoperative (a2, p = 0.802) collateral arteries, as well as BSR (p = 0.088) and RR (p = 0.592) between endo and surgical groups. There was also no significant difference in short-term clinical outcomes between the two groups.CONCLUSION:
Our limited series suggests that intraluminal stent implantation may not be inferior to surgical bypass grafting regarding the undifferentiated short-term clinical outcomes as well as the chosen hemodynamic surrogate parameters.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
/
2_ODS3
Problema de salud:
1_doencas_nao_transmissiveis
/
2_muertes_prematuras_enfermedades_notrasmisibles
Asunto principal:
Procedimientos Quirúrgicos Vasculares
/
Stents
/
Circulación Colateral
/
Implantación de Prótesis Vascular
/
Síndrome de Leriche
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
Límite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Cardiovasc Intervent Radiol
Año:
2021
Tipo del documento:
Article