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Evaluating the Sensitivity and Specificity of Promising Circulating Biomarkers to Diagnose Liver Injury in Humans.
Llewellyn, Heather P; Vaidya, Vishal S; Wang, Zhenyu; Peng, Qinghai; Hyde, Craig; Potter, David; Wang, Jianying; Zong, Qing; Arat, Seda; Martin, Matt; Masek-Hammerman, Katherine; Warner, Roscoe; Johnson, Kent; Kullak-Ublick, Gerd A; Aithal, Guruprasad P; Dear, James W; Ramaiah, Shashi K.
Afiliación
  • Llewellyn HP; Drug Safety Research and Development, Pfizer Inc., San Diego, CA, 92121 USA.
  • Vaidya VS; Drug Safety Research and Development, Pfizer Inc., Cambridge, MA 02139, USA.
  • Wang Z; Early Clinical Development, Pfizer, Inc., Cambridge, Massachusetts 02139, USA.
  • Peng Q; Drug Safety Research and Development, Pfizer Inc., San Diego, CA, 92121 USA.
  • Hyde C; Early Clinical Development, Pfizer, Inc., Cambridge, Massachusetts 02139, USA.
  • Potter D; Drug Safety Research and Development, Pfizer Inc., Cambridge, MA 02139, USA.
  • Wang J; Drug Safety Research and Development, Pfizer Inc., San Diego, CA, 92121 USA.
  • Zong Q; Drug Safety Research and Development, Pfizer Inc., San Diego, CA, 92121 USA.
  • Arat S; Drug Safety Research and Development, Pfizer Inc., Groton, CT 06340 USA.
  • Martin M; Drug Safety Research and Development, Pfizer Inc., Groton, CT 06340 USA.
  • Masek-Hammerman K; Drug Safety Research and Development, Pfizer Inc., Cambridge, MA 02139, USA.
  • Warner R; Michigan Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Johnson K; Michigan Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
  • Kullak-Ublick GA; Mechanistic Safety, CMO & Patient Safety, Global Drug Development, Novartis, Basel 4056, Switzerland.
  • Aithal GP; Department of Clinical Pharmacology and Toxicology, University Hospital Zurich, University of Zurich, Zurich 8091, Switzerland.
  • Dear JW; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham NG7 2UH, UK.
  • Ramaiah SK; Pharmacology, Therapeutics and Toxicology, Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK.
Toxicol Sci ; 181(1): 23-34, 2021 04 27.
Article en En | MEDLINE | ID: mdl-33483742

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: MicroARNs / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Toxicol Sci Asunto de la revista: TOXICOLOGIA Año: 2021 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: MicroARNs / Enfermedad Hepática Inducida por Sustancias y Drogas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans Idioma: En Revista: Toxicol Sci Asunto de la revista: TOXICOLOGIA Año: 2021 Tipo del documento: Article
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