A short deletion in the DNA-binding domain of STAT3 suppresses growth and progression of colon cancer cells.

Xiong, Yi-Jia; Liu, Dong-Yang; Shen, Rong-Rong; Xiong, Yong

Xiong, Yi-Jia; Liu, Dong-Yang; Shen, Rong-Rong; Xiong, Yong.

Afiliación

Xiong YJ; Department of Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Liu DY; Department of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China.
Shen RR; Department of General Surgery, Shanghai Sixth People's Hospital East Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai 201308, China.
Xiong Y; Department of General Surgery, Shanghai Sixth People's Hospital East Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai 201308, China.

Aging (Albany NY) ; 13(4): 5185-5196, 2021 02 01.

Article en En | MEDLINE | ID: mdl-33535185

Asunto(s)

Neoplasias Colorrectales/genética; Regulación Neoplásica de la Expresión Génica/genética; Factor de Transcripción STAT3/genética; Secuencia de Bases; Línea Celular Tumoral; Neoplasias Colorrectales/metabolismo; Células HCT116; Humanos; Mutación; Regiones Promotoras Genéticas; Dominios Proteicos/genética; Factor de Transcripción STAT3/metabolismo; Eliminación de Secuencia

Palabras clave

JAK/STAT pathway; STAT3; colon cancer; gain of function

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Regulación Neoplásica de la Expresión Génica / Factor de Transcripción STAT3 Límite: Humans Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2021 Tipo del documento: Article País de afiliación: China

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