Nanotomography of lesional skin using electron microscopy reveals cytosolic release of nuclear DNA in psoriasis.

Lindberg, Eric; Baumer, Yvonne; Stempinski, Erin S; Rodante, Justin A; Powell-Wiley, Tiffany M; Dey, Amit K; Nakajima, Saeko; Playford, Martin P; Bleck, Christopher K E; Mehta, Nehal N

Lindberg, Eric; Baumer, Yvonne; Stempinski, Erin S; Rodante, Justin A; Powell-Wiley, Tiffany M; Dey, Amit K; Nakajima, Saeko; Playford, Martin P; Bleck, Christopher K E; Mehta, Nehal N.

Afiliación

Lindberg E; Electron Microscopy Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Baumer Y; Electron Microscopy Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Stempinski ES; Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Rodante JA; Electron Microscopy Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Powell-Wiley TM; Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Dey AK; Social Determinants of Obesity and Cardiovascular Risk Laboratory, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Nakajima S; Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Playford MP; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Bleck CKE; Section of Inflammation and Cardiometabolic Diseases, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Mehta NN; Electron Microscopy Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.

JAAD Case Rep ; 9: 9-14, 2021 Mar.

Article en En | MEDLINE | ID: mdl-33598517

Palabras clave

DNA release; FIB-SEM; FIB-SEM, Focused Ion Beam Scanning Electron Microscopy; NHLBI, National Heart, Lung and Blood Institute; NIH, National Institutes of Health; SEM, scanning electron microscope; inflammation; keratinocytes; psoriasis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: JAAD Case Rep Año: 2021 Tipo del documento: Article