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Ligand Strain and Its Conformational Complexity Is a Major Factor in the Binding of Cyclic Dinucleotides to STING Protein.
Smola, Miroslav; Gutten, Ondrej; Dejmek, Milan; Kozísek, Milan; Evangelidis, Thomas; Tehrani, Zahra Aliakbar; Novotná, Barbora; Nencka, Radim; Birkus, Gabriel; Rulísek, Lubomír; Boura, Evzen.
Afiliación
  • Smola M; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Gutten O; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Dejmek M; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Kozísek M; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Evangelidis T; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Tehrani ZA; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Novotná B; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Nencka R; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Birkus G; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Rulísek L; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
  • Boura E; Gilead Sciences Research Centre at IOCB, Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Flemingovo námestí 2, 16610, Prague, Czech Republic.
Angew Chem Int Ed Engl ; 60(18): 10172-10178, 2021 04 26.
Article en En | MEDLINE | ID: mdl-33616279
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de la Membrana / Nucleótidos Cíclicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article País de afiliación: República Checa
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de la Membrana / Nucleótidos Cíclicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2021 Tipo del documento: Article País de afiliación: República Checa