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A synthetic diterpene analogue inhibits mycobacterial persistence and biofilm formation by targeting (p)ppGpp synthetases.
Tkachenko, Alexander G; Kashevarova, Natalya M; Sidorov, Roman Yu; Nesterova, Larisa Yu; Akhova, Anna V; Tsyganov, Ivan V; Vaganov, Vladimir Yu; Shipilovskikh, Sergei A; Rubtsov, Aleksandr E; Malkov, Andrei V.
Afiliación
  • Tkachenko AG; Laboratory of Microbial Adaptation, Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, Ural Branch, Goleva 13, Perm, 614081, Perm Krai, Russia; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia. Electronic address: agtkac
  • Kashevarova NM; Laboratory of Microbial Adaptation, Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, Ural Branch, Goleva 13, Perm, 614081, Perm Krai, Russia.
  • Sidorov RY; Laboratory of Microbial Adaptation, Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, Ural Branch, Goleva 13, Perm, 614081, Perm Krai, Russia; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia.
  • Nesterova LY; Laboratory of Microbial Adaptation, Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, Ural Branch, Goleva 13, Perm, 614081, Perm Krai, Russia; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia.
  • Akhova AV; Laboratory of Microbial Adaptation, Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, Ural Branch, Goleva 13, Perm, 614081, Perm Krai, Russia; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia.
  • Tsyganov IV; Laboratory of Microbial Adaptation, Institute of Ecology and Genetics of Microorganisms, Perm Federal Research Center, Russian Academy of Sciences, Ural Branch, Goleva 13, Perm, 614081, Perm Krai, Russia; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia.
  • Vaganov VY; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia.
  • Shipilovskikh SA; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia.
  • Rubtsov AE; Perm State University, Bukireva 15, Perm, 614990, Perm Krai, Russia. Electronic address: rubtsov@psu.ru.
  • Malkov AV; Department of Chemistry, Loughborough University Address: University Road, Loughborough, Leicestershire LE11 3TU, UK. Electronic address: a.malkov@lboro.ac.uk.
Cell Chem Biol ; 28(10): 1420-1432.e9, 2021 10 21.
Article en En | MEDLINE | ID: mdl-33621482
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_tuberculosis Asunto principal: Proteínas Bacterianas / Biopelículas / Mycobacterium smegmatis / Diterpenos / Ligasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 3_ND Problema de salud: 3_tuberculosis Asunto principal: Proteínas Bacterianas / Biopelículas / Mycobacterium smegmatis / Diterpenos / Ligasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Chem Biol Año: 2021 Tipo del documento: Article