Conventional vs high-sensitive troponins in acute exacerbations of chronic obstructive pulmonary disease.
Heart Lung
; 50(3): 430-436, 2021.
Article
en En
| MEDLINE
| ID: mdl-33621841
ABSTRACT
BACKGROUND:
Cardiac troponins (cTn), either conventional or high-sensitive (hscTn) assays, are often performed during acute exacerbations of chronic obstructive pulmonary disease (AECOPD).OBJECTIVES:
To compare factors affecting abnormal conventional cTn and hscTn.METHODS:
We retrospectively studied data from AECOPD patients with conventional or hscTn performed at presentation. Binary logistic regression was used to identify predictors for abnormal conventional cTn (>0.5 ug/L) and hscTn (>40 ng/L).RESULTS:
There were 466 patients in the conventional cTn and 313 patients in the hscTn groups. Ischaemic electrocardiographic change was the only significant predictor for abnormal conventional cTn (OR 6.662 [CI 1.233-35.990], p = 0.028) while B-type natriuretic peptide levels (Adj OR 1.004 [CI 1.000-1.006], p = 0.010) and SpO2/FiO2 ratio (Adj OR 0.115 [CI 0.017-0.069], p = 0.026) were significant predictors of abnormal hscTn.CONCLUSIONS:
Predictors of abnormal cTn differ between assays and should be taken into consideration when interpreting cTn during AECOPD.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Troponina
/
Enfermedad Pulmonar Obstructiva Crónica
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Heart Lung
Año:
2021
Tipo del documento:
Article