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Identification of CYP2D6 Haplotypes that Interfere with Commonly Used Assays for Copy Number Variation Characterization.
Turner, Amy J; Aggarwal, Praful; Boone, Erin C; Haidar, Cyrine-Eliana; Relling, Mary V; Derezinski, Ashley D; Broeckel, Ulrich; Gaedigk, Andrea.
Afiliación
  • Turner AJ; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; Right Patient Right Drug Diagnostics, Wauwatosa, Wisconsin.
  • Aggarwal P; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; Right Patient Right Drug Diagnostics, Wauwatosa, Wisconsin.
  • Boone EC; Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy Kansas City, University of Missouri-Kansas City, Kansas City, Missouri.
  • Haidar CE; Pharmaceutical Science Department, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Relling MV; Pharmaceutical Science Department, St. Jude Children's Research Hospital, Memphis, Tennessee.
  • Derezinski AD; Right Patient Right Drug Diagnostics, Wauwatosa, Wisconsin.
  • Broeckel U; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; Right Patient Right Drug Diagnostics, Wauwatosa, Wisconsin.
  • Gaedigk A; Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy Kansas City, University of Missouri-Kansas City, Kansas City, Missouri. Electronic address: agaedigk@cmh.edu.
J Mol Diagn ; 23(5): 577-588, 2021 05.
Article en En | MEDLINE | ID: mdl-33631352
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Haplotipos / Reacción en Cadena de la Polimerasa / Citocromo P-450 CYP2D6 / Variaciones en el Número de Copia de ADN / Secuenciación de Nucleótidos de Alto Rendimiento Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: J Mol Diagn Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Polimorfismo Genético / Haplotipos / Reacción en Cadena de la Polimerasa / Citocromo P-450 CYP2D6 / Variaciones en el Número de Copia de ADN / Secuenciación de Nucleótidos de Alto Rendimiento Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: J Mol Diagn Asunto de la revista: BIOLOGIA MOLECULAR Año: 2021 Tipo del documento: Article