PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by <i>Pseudomonas aeruginosa</i>.

McMahon, Derek B; Carey, Ryan M; Kohanski, Michael A; Adappa, Nithin D; Palmer, James N; Lee, Robert J

PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa.

McMahon, Derek B; Carey, Ryan M; Kohanski, Michael A; Adappa, Nithin D; Palmer, James N; Lee, Robert J.

Afiliación

McMahon DB; Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Carey RM; Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Kohanski MA; Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Adappa ND; Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Palmer JN; Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Lee RJ; Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Am J Physiol Lung Cell Mol Physiol ; 320(5): L845-L879, 2021 05 01.

Article en En | MEDLINE | ID: mdl-33655758

Asunto(s)

Cloruros/metabolismo; Regulador de Conductancia de Transmembrana de Fibrosis Quística/metabolismo; Glándulas Exocrinas/patología; Infecciones por Pseudomonas/microbiología; Receptor PAR-2/metabolismo; Mucosa Respiratoria/patología; Membrana Serosa/patología; Calcio/metabolismo; Células Cultivadas; AMP Cíclico/metabolismo; Glándulas Exocrinas/metabolismo; Glándulas Exocrinas/microbiología; Humanos; Pseudomonas aeruginosa/aislamiento & purificación; Mucosa Respiratoria/metabolismo; Mucosa Respiratoria/microbiología; Membrana Serosa/metabolismo; Membrana Serosa/microbiología

Palabras clave

airway surface liquid; antimicrobial peptide; chronic rhinosinusitis; cilia; cystic fibrosis

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Infecciones por Pseudomonas / Membrana Serosa / Cloruros / Regulador de Conductancia de Transmembrana de Fibrosis Quística / Mucosa Respiratoria / Receptor PAR-2 / Glándulas Exocrinas Límite: Humans Idioma: En Revista: Am J Physiol Lung Cell Mol Physiol Asunto de la revista: BIOLOGIA MOLECULAR / FISIOLOGIA Año: 2021 Tipo del documento: Article

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