CDC25B induces cellular senescence and correlates with tumor suppression in a p53-dependent manner.

Chen, Ying-Chieh; Hsieh, Hsi-Hsien; Chang, Hsi-Chi; Wang, Hsin-Chiao; Lin, Wey-Jinq; Lin, Jing-Jer

Chen, Ying-Chieh; Hsieh, Hsi-Hsien; Chang, Hsi-Chi; Wang, Hsin-Chiao; Lin, Wey-Jinq; Lin, Jing-Jer.

Afiliación

Chen YC; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan.
Hsieh HH; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan.
Chang HC; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan.
Wang HC; Institute of Biochemistry and Molecular Biology, National Taiwan University College of Medicine, Taipei, Taiwan.
Lin WJ; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan. Electronic address: wjlin@ym.edu.tw.
Lin JJ; Institute of Biopharmaceutical Sciences, National Yang-Ming University, Taipei, Taiwan; Institute of Biochemistry and Molecular Biology, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address: jingjerlin@ntu.edu.tw.

J Biol Chem ; 296: 100564, 2021.

Article en En | MEDLINE | ID: mdl-33745968

Asunto(s)

Senescencia Celular; Proteína p53 Supresora de Tumor/metabolismo; Ciclo Celular; Línea Celular Tumoral; Daño del ADN; Humanos

Palabras clave

CDC25B; p53; phosphatase; senescence; tumor suppression

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Senescencia Celular Límite: Humans Idioma: En Revista: J Biol Chem Año: 2021 Tipo del documento: Article País de afiliación: Taiwán

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