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Discovery of novel tetrahydrobenzo[b]thiophene-3-carbonitriles as histone deacetylase inhibitors.
Gediya, Piyush; Vyas, Vivek K; Carafa, Vincenzo; Sitwala, Nikum; Della Torre, Laura; Poziello, Angelita; Kurohara, Takashi; Suzuki, Takayoshi; Sanna, Vinod; Raguraman, Varalakshmi; Suthindhiran, K; Ghosh, Debarpan; Bhatia, Dhiraj; Altucci, Lucia; Ghate, Manjunath D.
Afiliación
  • Gediya P; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India.
  • Vyas VK; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India.
  • Carafa V; Department of Precision Medicine, Università degli Studi della Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.
  • Sitwala N; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India.
  • Della Torre L; Department of Precision Medicine, Università degli Studi della Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.
  • Poziello A; Department of Precision Medicine, Università degli Studi della Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy.
  • Kurohara T; The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibarakishi, Osaka 567-0047, Japan.
  • Suzuki T; The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibarakishi, Osaka 567-0047, Japan.
  • Sanna V; Piramal Pharma Solution, Plot-18 Pharmaceutical Special Economic Zone, Sarkhej-Bawla, NH-8A, Ahmedabad, Gujarat 382213, India.
  • Raguraman V; School of Bio-Sciences and Technology, Vellore Institute of Technology, Vellore, Tamilnadu, India.
  • Suthindhiran K; School of Bio-Sciences and Technology, Vellore Institute of Technology, Vellore, Tamilnadu, India.
  • Ghosh D; Department of Biological Engineering, Indian Institute of Technology, Gandhinagar 382355, Gujarat, India.
  • Bhatia D; Department of Biological Engineering, Indian Institute of Technology, Gandhinagar 382355, Gujarat, India.
  • Altucci L; Department of Precision Medicine, Università degli Studi della Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy. Electronic address: lucia.altucci@unicampania.it.
  • Ghate MD; Department of Pharmaceutical Chemistry, Institute of Pharmacy, Nirma University, Ahmedabad 382481, Gujarat, India. Electronic address: manjunath.ghate@nirmauni.ac.in.
Bioorg Chem ; 110: 104801, 2021 05.
Article en En | MEDLINE | ID: mdl-33756235
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiofenos / Descubrimiento de Drogas / Inhibidores de Histona Desacetilasas / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: India
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tiofenos / Descubrimiento de Drogas / Inhibidores de Histona Desacetilasas / Antineoplásicos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2021 Tipo del documento: Article País de afiliación: India