Circular RNA hsa_circ_0072309 inhibits the proliferation, invasion and migration of gastric cancer cells via inhibition of PI3K/AKT signaling by activating PPARÎ³/PTEN signaling.

Guo, Xingpo; Qin, Mingde; Hong, Han; Xue, Xiaofeng; Fang, Jian; Jiang, Linhua; Kuang, Yuting; Gao, Ling

Guo, Xingpo; Qin, Mingde; Hong, Han; Xue, Xiaofeng; Fang, Jian; Jiang, Linhua; Kuang, Yuting; Gao, Ling.

Afiliación

Guo X; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, P.R. China.
Qin M; The Stem Cell and Biomedical Material Key Laboratory of Jiangsu Province (The State Key Laboratory Incubation Base), Soochow University, Suzhou, Jiangsu 215000, P.R. China.
Hong H; Department of HepatoPancreatoBiliary Surgery, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou, Jiangsu 215000, P.R. China.
Xue X; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, P.R. China.
Fang J; Department of General Surgery, Zhangjiagang Hospital Affiliated to Soochow University, Zhangjiagang, Jiangsu 215600, P.R. China.
Jiang L; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, P.R. China.
Kuang Y; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, P.R. China.
Gao L; Department of General Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215000, P.R. China.

Mol Med Rep ; 23(5)2021 05.

Article en En | MEDLINE | ID: mdl-33760104

Asunto(s)

PPAR gamma/genética; Fosfohidrolasa PTEN/genética; ARN Circular/genética; Neoplasias Gástricas/genética; Línea Celular Tumoral; Movimiento Celular/genética; Proliferación Celular/genética; Regulación Neoplásica de la Expresión Génica/genética; Humanos; Invasividad Neoplásica/genética; Invasividad Neoplásica/patología; Fosfatidilinositol 3-Quinasas/genética; Proteínas Proto-Oncogénicas c-akt/genética; Transducción de Señal/genética; Neoplasias Gástricas/patología

Palabras clave

gastric cancer; hsa_circ_0072309; PI3K/AKT; mTOR; peroxisome proliferatoractivated receptor Î³/PTEN

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Gástricas / PPAR gamma / Fosfohidrolasa PTEN / ARN Circular Límite: Humans Idioma: En Revista: Mol Med Rep Año: 2021 Tipo del documento: Article

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