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Functional brain imaging in larval zebrafish for characterising the effects of seizurogenic compounds acting via a range of pharmacological mechanisms.
Winter, Matthew J; Pinion, Joseph; Tochwin, Anna; Takesono, Aya; Ball, Jonathan S; Grabowski, Piotr; Metz, Jeremy; Trznadel, Maciej; Tse, Karen; Redfern, Will S; Hetheridge, Malcolm J; Goodfellow, Marc; Randall, Andrew D; Tyler, Charles R.
Afiliación
  • Winter MJ; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Pinion J; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Tochwin A; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Takesono A; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Ball JS; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Grabowski P; Data Science and Artificial Intelligence, Clinical Pharmacology & Safety Sciences, AstraZeneca R&D, Cambridge, UK.
  • Metz J; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Trznadel M; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Tse K; Safety & Mechanistic Pharmacology, Clinical Pharmacology & Safety Sciences, AstraZeneca R&D, Cambridge, UK.
  • Redfern WS; Sovereign House, GW Pharmaceuticals plc, Cambridge, UK.
  • Hetheridge MJ; Safety & Mechanistic Pharmacology, Clinical Pharmacology & Safety Sciences, AstraZeneca R&D, Cambridge, UK.
  • Goodfellow M; Simcyp Division, Certara UK Limited, Sheffield, UK.
  • Randall AD; Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, Devon, UK.
  • Tyler CR; Department of Mathematics & Living Systems Institute and EPSRC Centre for Predictive Modelling in Healthcare, University of Exeter, Exeter, Devon, UK.
Br J Pharmacol ; 178(13): 2671-2689, 2021 07.
Article en En | MEDLINE | ID: mdl-33768524

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pez Cebra / Encéfalo Aspecto: Ethics Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pez Cebra / Encéfalo Aspecto: Ethics Límite: Animals Idioma: En Revista: Br J Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
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