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The AMPK modulator metformin as adjunct to methotrexate in patients with rheumatoid arthritis: A proof-of-concept, randomized, double-blind, placebo-controlled trial.
Abdallah, Mahmoud S; Alarfaj, Sumaiah J; Saif, Dalia S; El-Naggar, Mostafa E; Elsokary, Mohamed A; Elsawah, Hozaifa K; Abdelsattar Zaki, Shimaa; Wahsh, Engy A; Abo Mansour, Hend E; Mosalam, Esraa M.
Afiliación
  • Abdallah MS; Department of Clinical Pharmacy, Faculty of Pharmacy, University of Sadat City, Sadat City, Menoufia 32897, Egypt. Electronic address: Mahmoud.samy@fop.usc.edu.eg.
  • Alarfaj SJ; Department of Pharmacy Practice, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Saudi Arabia.
  • Saif DS; Department of Physical Medicine, Rheumatology and Rehabilitation, Faculty of Medicine, Menoufia University, Menoufia, Egypt.
  • El-Naggar ME; Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Sadat City, Menoufia, Egypt.
  • Elsokary MA; Department of Biostatistics, High Institute of Public Health, Alexandria University, Alexandria, Egypt.
  • Elsawah HK; Department of Biostatistics, High Institute of Public Health, Alexandria University, Alexandria, Egypt.
  • Abdelsattar Zaki S; Department of Clinical Biochemistry and Molecular Diagnostics, National Liver Institute, Menoufia University, Egypt.
  • Wahsh EA; Department of Clinical Pharmacy, Faculty of Pharmacy, October 6 University, Egypt.
  • Abo Mansour HE; Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Egypt.
  • Mosalam EM; Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Egypt.
Int Immunopharmacol ; 95: 107575, 2021 Jun.
Article en En | MEDLINE | ID: mdl-33773207
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Artritis Reumatoide / Adyuvantes Inmunológicos / Metotrexato / Antirreumáticos / Proteínas Quinasas Activadas por AMP / Metformina Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_doencas_nao_transmissiveis Asunto principal: Artritis Reumatoide / Adyuvantes Inmunológicos / Metotrexato / Antirreumáticos / Proteínas Quinasas Activadas por AMP / Metformina Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Int Immunopharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Año: 2021 Tipo del documento: Article