Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: A controlled before-and-after trial.
Elife
; 102021 04 09.
Article
en En
| MEDLINE
| ID: mdl-33835026
ABSTRACT
We conducted a controlled before-and-after trial to evaluate the impact of an onsite urban sanitation intervention on the prevalence of enteric infection, soil transmitted helminth re-infection, and diarrhea among children in Maputo, Mozambique. A non-governmental organization replaced existing poor-quality latrines with pour-flush toilets with septic tanks serving household clusters. We enrolled children aged 1-48 months at baseline and measured outcomes before and 12 and 24 months after the intervention, with concurrent measurement among children in a comparable control arm. Despite nearly exclusive use, we found no evidence that intervention affected the prevalence of any measured outcome after 12 or 24 months of exposure. Among children born into study sites after intervention, we observed a reduced prevalence of Trichuris and Shigella infection relative to the same age group at baseline (<2 years old). Protection from birth may be important to reduce exposure to and infection with enteric pathogens in this setting.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Contexto en salud:
1_ASSA2030
/
2_ODS3
/
3_ND
/
4_TD
Problema de salud:
1_doencas_transmissiveis
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2_cobertura_universal
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2_enfermedades_transmissibles
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2_quimicos_contaminacion
/
3_diarrhea
/
3_helminthiasis
/
3_neglected_diseases
/
3_zoonosis
/
4_diarrhoeal_infections
Asunto principal:
Cuartos de Baño
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Infecciones Bacterianas
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Ingeniería Sanitaria
/
Salud Urbana
/
Helmintiasis
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
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Prevalence_studies
/
Risk_factors_studies
Límite:
Child, preschool
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Female
/
Humans
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Infant
/
Male
País/Región como asunto:
Africa
Idioma:
En
Revista:
Elife
Año:
2021
Tipo del documento:
Article
País de afiliación:
Reino Unido