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Tuning Proton Transfer Thermodynamics in SARS-CoV-2 Main Protease: Implications for Catalysis and Inhibitor Design.
Zanetti-Polzi, Laura; Smith, Micholas Dean; Chipot, Chris; Gumbart, James C; Lynch, Diane L; Pavlova, Anna; Smith, Jeremy C; Daidone, Isabella.
Afiliación
  • Zanetti-Polzi L; Center S3, CNR Institute of Nanoscience, Via Campi 213/A, I-41125 Modena, Italy.
  • Smith MD; Department of Biochemistry, Molecular and Cellular Biology, The University of Tennessee, Knoxville, 309 Ken and Blaire Mossman Bldg., 1311 Cumberland Avenue, Knoxville, Tennessee 37996, United States.
  • Chipot C; UMR 7019, Université de Lorraine, Laboratoire International Associé CNRS, 54506 Vandœuvre-lès-Nancy, France.
  • Gumbart JC; University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, Illinois 61801, United States.
  • Lynch DL; School of Physics, Georgia Institute of Technology, Atlanta Georgia 30332, United States.
  • Pavlova A; School of Physics, Georgia Institute of Technology, Atlanta Georgia 30332, United States.
  • Smith JC; School of Physics, Georgia Institute of Technology, Atlanta Georgia 30332, United States.
  • Daidone I; Department of Biochemistry, Molecular and Cellular Biology, The University of Tennessee, Knoxville, 309 Ken and Blaire Mossman Bldg., 1311 Cumberland Avenue, Knoxville, Tennessee 37996, United States.
J Phys Chem Lett ; 12(17): 4195-4202, 2021 May 06.
Article en En | MEDLINE | ID: mdl-33900080

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 4_TD Problema de salud: 4_pneumonia Asunto principal: Inhibidores de Proteasas / Diseño de Fármacos / Proteínas de la Matriz Viral / SARS-CoV-2 Límite: Humans Idioma: En Revista: J Phys Chem Lett Año: 2021 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 4_TD Problema de salud: 4_pneumonia Asunto principal: Inhibidores de Proteasas / Diseño de Fármacos / Proteínas de la Matriz Viral / SARS-CoV-2 Límite: Humans Idioma: En Revista: J Phys Chem Lett Año: 2021 Tipo del documento: Article País de afiliación: Italia
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