Palladium-catalyzed carbonylative cyclization of benzyl chlorides with anthranils for the synthesis of 3-arylquinolin-2(1<i>H</i>)-ones.

Liu, Jian-Li; Xu, Ren-Rui; Wang, Wei; Qi, Xinxin; Wu, Xiao-Feng

Palladium-catalyzed carbonylative cyclization of benzyl chlorides with anthranils for the synthesis of 3-arylquinolin-2(1H)-ones.

Liu, Jian-Li; Xu, Ren-Rui; Wang, Wei; Qi, Xinxin; Wu, Xiao-Feng.

Afiliación

Liu JL; Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, People's Republic of China. xinxinqi@zstu.edu.cn.
Xu RR; Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, People's Republic of China. xinxinqi@zstu.edu.cn.
Wang W; Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, People's Republic of China. xinxinqi@zstu.edu.cn.
Qi X; Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, People's Republic of China. xinxinqi@zstu.edu.cn.
Wu XF; Dalian National Laboratory for Clean Energy, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 116023, Dalian, Liaoning, China. xwu2020@dicp.ac.cn and Leibniz-Institut für Katalyse e.V. an der, Institution Universität Rostock, Albert-Einstein-Straße 29a, Rostock 18059, Germany. xiao

Org Biomol Chem ; 19(16): 3584-3588, 2021 04 28.

Article en En | MEDLINE | ID: mdl-33908566

RESUMEN

An efficient carbonylative procedure for the synthesis of 3-arylquinoin-2(1H)-ones has been established. Through a palladium-catalyzed aminocarbonylation of benzyl chlorides with anthranils, a variety of 3-arylquinoin-2(1H)-one products were obtained in moderate to excellent yields with good functional group tolerance.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Org Biomol Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article

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